Mefoxin Injectable and/or Equivalents
Drug | Related Drug Names |
---|---|
Mefoxin Injectable 1g and/or Equivalents | Cefoxitin Injection, Cefoxitin Vial Injectable |
Mefoxin Injectable
Mefoxin Injectable Drug Description
Mefoxin (Cefoxitin Injection) belongs to the Cephalosporin group of antibiotics and is primarily used for the treatment of numerous types of bacterial infestations or infections, many of which are life threatening. Mefoxin is a broad-spectrum cephalexin antibiotic that is manufactured, marketed and distributed by Merck & Co., Inc. and the registered trademark for the formulation belongs to Bioniche Teoranta. It is supplied in hermetically sealed condition (containing nitrogen) and is administered intravenously. It is a derivative of cephamycin C which in turn is obtained from the microorganism Streptomyces Lactamdurans. Mefoxin as an antibiotic is used across the board for an extensive assortment of bacterial contaminations. It is also administered to patients as a pre and post surgical antibiotic for the prevention of infections. It is highly effective in inhibiting the growth and development of certain types of aerobic and anaerobic microorganisms. Mefoxin has about 53.8 mg of sodium for every gram of cefoxitin. Mefoxin solutions are usually colourless and some preparations are amber coloured. The pH (acidity or alkalinity) of a fresh solution generally varies from 4.2-7.0. The molecular weight of Cefoxitin Sodium is 449.44. Every 50 ml solution of Mefoxin contains cefoxitin sodium which is the main active ingredient and Dextrous Hydrous USP is added for the sake of osomolality. The acidity or alkalinity is adjusted and set in sync with the pH of sodium bicarbonate and hydrochloric acid that are inactive. The ampoules containing the solution, are made from multilayered plastic, and are sufficiently sterilized so that the chemicals components are able to retain their effectiveness over their active life cycle.
Conditions treated by Mefoxin Injectable
Mefoxin is prescribed by physicians as a prophylactic antibiotic for a wide swathe of bacterial infections many of which can take a turn for the worse and become fatal. It is approved for infections in the lower respiratory region like pneumonia, influenza, lung abscess and bronchitis. It is widely prescribed for contagions in the urinary tract, abdomen and intra-abdominal region infestations like peritonitis and ulcerative colitis, endometritis, and pelvic cellulitis (gynaecological), septicaemia, several joint and bone infestations, and dermal infections. Suitable culture and sensitivity studies are carried out to evaluate the susceptibility and responsiveness of the relevant strains of bacteria to Mefoxin before a patient is prescribed an antibiotic course of the same.
Mefoxin Injectable Dosage Information
a) Typical Dosage recommendations
Mefoxin is administered intravenously or intramuscularly (subcutaneous) by a disposable syringe. The dosage is determined according to your medical state, your responsiveness to the medication course and the acuteness or degree of infection. The normal dosage range for an adult is 1-2 grams and is given 3 to 4 times a day. Adults having renal insufficiency or whose renal functionality is impaired can be infused with 1-2 grams of the cefoxitin formulation initially and depending on the response, the regular dosage level can be worked out. Patients on haemodialysis a 1-2 grams loadable dose can be administered after each procedure. New born babies (not less than three months of age) and older children can be given between six and eight doses in a day and the dosage level is 80-160 mg/kg according to body weight. For neonatal babies and children with severe infections higher dosage levels are recommended but the entire dosage on a daily basis should never be more than 12 grams in any case. For operations and surgeries, 2 grams of Mefoxin is administered into the veins about an hour prior to the procedure. And thereafter the same dosage is given after every six hours following the first dosage. Dosages must be discontinued within 24 hours of the operation.
b) Missing a dose
If you’ve have been prescribed Mefoxin by your doctor for the treatment of a bacterial infection, then you should use the medication exclusively for the purpose you’ve been recommended and not for any other type of illness or ailment. For instance, you cannot use Mefoxin for the treatment of any viral condition like common cold. If you forget to take a dose, then you should take it the moment you remember that you’ve missed it. And if you recall missing a dose when it’s virtually time for your next scheduled dose, then it is better to skip it and carry on with your regular dosages. Do not try to make up for the missed dose by increasing your intake in the subsequent dosage. Missing doses more often may interfere with the effectiveness of the medication as far as susceptibility to treatment is concerned.
c) Overdosing
You might experience symptoms of seizure and may have paroxysms if you accidently inject an overdose of Mefoxin. Needless to say, you’d have to go for emergency medical relief. Warnings Before you can get started on a course of Mefoxin, you’d need to inform your doctor about your ongoing medications, particularly generic antibiotic drugs like cefoxitin, cephalosporin, and penicillin. Many patients are extremely hypersensitive and allergic to antibiotics including Mefoxin. CDAD (clostridium difficule associated bacteria) is a usual allergic reaction and common side effect associated with long term use of Mefoxin and almost all other antibiotics that causes mild to severe diarrhoea and even acute colitis that can be fatalistic. If you have symptoms of CDAD after taking the medication, you should immediately stop taking further dosages and get in touch with your doctor as soon as possible. You should also take electrolytic fluids and protein supplementations to tackle dehydration.
Mefoxin Injectable Side effects
If you notice symptoms of any allergic reaction like shortness of breath, hives, redness or swelling of the face, mouth or throat, you should seek medical intervention without delay. You should also get in touch with your physician if you exhibit the following side effects:
- Watery or bloody diarrhea
- Jaundice
- Convulsions
- Infrequent or decreased urination
- Fevers, body aches, chills, signs of flu, and chills
- Bruising or bleeding easily
- Feeling unusually tired
- Dizziness and fainting
- Skin rashes, acute tingling, muscular spasms and weakness, and numbness
- Abdominal pain
- Vomiting
- Nausea
- Vaginal discharges and itchiness
The above list is not exhaustive and you might experience other side effects as well.
Mefoxin Injectable Drug interactions
When you visit your doctor for a consultation, bring to his notice if you’re using the following antibiotics:
- Streptomycin
- Penicillin
- Nebcin
- Tobi
- Netromycin
- Neomycins including Mycifradin and Neo-Tab
- Kantrex
- Gentamycin
- Amikacin
Again this listing is not comprehensive. Let your doctor know about all vitamins, herbal products, protein supplements and other prescription medications you’re on. Always inform your physician before you take a new medicine.
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Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.
Mefoxin Injectable and/or Equivalents warnings, side-effects and general information