Norpramin and/or Equivalents

Drug	Related Drug Names
Norpramin 10mg and/or Equivalents	Desipramine
Norpramin 25mg and/or Equivalents	Desipramine
Norpramin 50mg and/or Equivalents	Desipramine
Norpramin 75mg and/or Equivalents	Desipramine
Norpramin 100mg and/or Equivalents	Desipramine

Norpramin

Norpramin Drug Description

Norpramin is the brand name for the generic drug Desipramine used for treating depression and mood disorders. It is a tricyclic antidepressant used for treating cocaine withdrawal symptoms, ADD, ADHD and neuropathic pain. Its function is to inhibit the re-uptake of serotonin (to some extent) and norepinephrine to a greater extent. Norpramin or Desipramine was once the first line of treatment for depression and mood disorders but has become the second resort ever since SSRI antidepressants were introduced. However, Norpramin or Desipramine is highly effective in blocking pain signals that try to ascend to the human brain through the spinal cord pathway.

Conditions Treated by Norpramin

Desipramine or Norpramin may be prescribed for treating substance related disorders, depressive disorder, attention deficit hyperactivity disorder and neuropathic pain.

Norpramin Dosage Information

a.) Typical Dosage Recommendations

Doctors recommend 100 to 200 mg of Norpramin every day for treating depression in adults. Elderly people or teenagers are usually prescribed with 25 to 100 mg of Norpramin each day. You can either take the dose all together (with food to prevent stomach upsets), preferably at night before going to bed or divide the prescribed dose into several smaller doses which you have to take all through the day.

b.) Missing a Dose

If you take Norpramin at night to prevent drowsiness and dizziness and miss a dose, skip the missed dose and take it next night following your usual dosing schedule. Double doses taken at once can result in death or coma.

c.) Overdosing

Because Norpramin overdose can possibly cause death, coma, cardiac shock, convulsions or other extremely fatal symptoms, you should take the patient to your nearest ER or call your local poison control helpline or local emergency number if you suspect an overdose.

Norpramin Warnings

Patients who have a family history of sudden cardiac deaths or dysrhythmias should use caution before taking Norpramin or Desipramine hydrochloride. Physicians in turn should screen patients for cardiac conduction disturbances and cardiac dysrhythmias before prescribing this medication. Overdoses of Norpramin can likely cause death due to cardiac dysrhythmias preceded by seizures. So patients should follow the dosage instructions very carefully.

Norpramin Side Effects

Some common side effects of Norpramin are:

• Dry mouth
• Constipation
• Weight gain
• Increased appetite
• Blurred vision
• Difficulty in sleeping
• Nervousness
• Drowsiness
• Dizziness
• Nausea
• Headache

Most of the side effects of Norpramin aren’t serious, nor do all patients taking this medicine suffer from these side effects. But if the side effect symptoms worsen or persist, you should contact your doctor immediately. Listed below are some rare but troublesome side effects of Norpramin that call for medical intervention:

• Trouble with urination
• Swelling or redness or pain in your legs and arms
• Tingling or numbness in the feet or hands
• Tremors
• Shakiness
• Sudden change in sexual urge
• Reduced sexual prowess
• Ringing in the ears
• Muscle stiffness
• Painful menstruation
• Irregular menstrual bleeding
• Unusual production of breast milk
• Painful, sore breasts
• Enlarged breasts
• Memory problems
• Hallucinations
• Depression
• Confusion
• Mood or mental changes

Following are a few very severe but rare side effects of Norpramin. Notify your health care provider immediately if you experience any of the following:

• Yellowing of the skin and eyes
• Dark urine
• Severe abdominal or stomach pain
• Persistent sore throat
• Fever
• Other signs of infection
• Easy bleeding and bruising
• Vision changes
• Weakness or paralysis on only one side of your body
• Slurred speech
• Fainting
• Seizures
• Irregular or fast or slow heartbeat
• Chest pain
• Serotonin toxicity or serotonin syndrome (if you take other medications that maximize serotonin levels)
• Restlessness
• Unusual agitation
• Unexplained fever
• Twitching muscles
• Diarrhoea
• Vomiting
• Severe nausea
• Severe dizziness
• Loss of coordination
• Hallucinations
• Fast heartbeat
• Alteration in the amount of urine
• Rashes
• Itching
• Hives
• Difficulty in breathing
• Swelling of the throat or lips or tongue or face

Seek medical attention right away if you notice or experience any of these very serious and often fatal symptoms described above.

Norpramin Drug Interactions

Common drug interactions include:

• Acetaminophen
• Aspirin
• Phenylpropanolamine
• Caffeine
• Codeine
• Valporic acid
• Thyroid supplements
• Levodopa
• Digoxin
• Medications for controlling high blood pressure
• Reserpine
• Guanethidine
• Guanadrel
• Clonidine
• Benztropine
• Medications for controlling Parkinson’s disease
• Scopolamine
• Belladonna alkaloids
• Atropine
• Anticholinergics
• Disopyramide
• MAO inhibitors
• Tranylcypromine
• Selegiline
• Rasagiline
• Procarbazine
• Phenelzine
• Moclobemide
• Methylene blue
• Linezolid
• Isocarboxazid
• St John’s Wort
• Ecstasy or MDMA
• Venlafaxine
• Duloxetine
• SNRI
• Paroxetine
• Fluoxetine
• SSRI
• Other types of antidepressants
• Phenobarbital alcohol
• Trazodone
• Anti seizure drugs
• Phenytoin
• Carbamazepine
• Pimozide
• Thioridazine
• Phenothiazines
• Fosamprenavir
• HIV protease inhibitors
• Halofantrine
• Propafenone
• Flecainide
• Drugs for controlling heart rhythm
• Haloperidol
• Cisapride
• Cimetidine
• Terbinafine

The above is not an exhaustive list of drugs that may interact with Norpramin. There are at least 927 generic drugs that can interact with Norpramin and lead to potentially deadly results or they may reduce the efficacy of this medication. You must provide your doctor or pharmacist a list of all the medications you are currently taking. This includes prescription drugs, over the counter medicines, herbal pills, health supplements, multi minerals and multivitamin supplements, weight loss pills, antacids and herbal products. Do not smoke tobacco/cigarettes or drink alcohol/ethanol while taking Norpramin. Norpramin also interacts with nine diseases:

• Tardive Dyskinesia
• Bipolar disorder
• Schizophrenia
• Liver disease or renal problems
• Diabetes
• Bone marrow suppression
• Seizure disorders
• Pheochromocytoma
• Cardiovascular ailments
• Anticholinergics effects such as urine retention, intraocular hypertension, glaucoma, GI obstruction

If you have any questions about buying discount Norpramin online or any other prescription products you can contact our team of professional Patient Service Representatives or one of our pharmacists 24-7 by calling 1-800-226-3784.

Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

Norpramin and/or Equivalents warnings, side-effects and general information