Uloric and/or Equivalents

Uloric(Febuxostat)

Uloric Description

Uloric is the brand name of a medicine that acts as an inhibitor of Xanthine oxidase in order to reduce uric acid production in the human body. Uric acid is a naturally occurring substance that is present in the body as a result of purine (a muscle protein) metabolism. Since humans lack the enzyme uricase needed for uric acid breakdown, the acid is normally excreted through the kidneys or intestines. However, certain physical conditions results in an excessive accumulation of this insoluble acid in the joints, tendons and cartilages leading to gout. The primary ingredient in Uloric is febuxostat. It also contains other inactive ingredients like microcrystalline cellulose, lactose monohydrate, sodium croscarmellose, silicone dioxide, hydroxypropyl cellulose, opadry II green and magnesium stearate. The medication is presented as tablets in two strengths of 40mg and 80mg though in Canada, the 80mg variant is commonly prescribed in gouty conditions. This light green coloured FDA approved tablet is tear-shaped with ‘TAP’ embossed on one side and ‘80’ embossed on the other side. It is presented by Takeda Canada, Inc. and is available in HDPE (high-density polyethylene) bottles containing thirty tablets each.

Conditions Treated by Uloric

Uloric is prescribed as a treatment for chronic gout associated with hyperuricaemia or the excessive accumulation of uric acid in the joints, leading to gouty conditions. The medicine works by lowering the levels of uric acid which is achieved by inhibiting the production of xanthine oxidase, an enzyme associated with purine metabolism. It is not prescribed as a treatment for high levels of uric acid in the absence of gout.

Uloric Dosage Information

a.) Typical dosage recommendations

The standard dose of Uloric is 80mg once daily or as advised by your medical caregiver. The medicine should be taken orally and about the same time everyday so that you don’t miss out on a particular dose. It can be taken before or after your meals and you can also take antacids if required. Your physician may alter the dose depending on your tolerance level and response to treatment. After starting your treatment with Uloric, you may see a flare-up in your gouty conditions which is due to a reduction in the level of serum uric acids. Speak to your physician for remedial methods but do not stop taking the medication. Your physician may then co-prescribe other medications like NSAIDs to reduce the pain.

b.) Missing a dose

In case you have missed taking your daily dose of Uloric, it is best to take the tablet as soon as you remember. However, taking the medicine in excess is not recommended so do not take two tablets at a time in order to compensate for a missed dose. Rather, it is better to skip a missed dose if you are about to take the next tablet as scheduled.

c.) Overdosing

Uloric is a relatively safe medicine and no life-threatening conditions have been reported with overdosing. In case you have overdose, contact your physician or nearest poison control centre for symptomatic treatment and support.

Uloric Warnings

Before starting your treatment with Uloric, discuss thoroughly with your doctor all the risks and benefits associated with the medicine. Share all information about your past and present health condition or about any other medicine that you are taking so that your physician can take the best decision. Your physician must know if you are allergic to febuxostat or any of the inactive ingredients present in the medicine. Always inform your doctor if you experience any flare-up in your gout after taking Uloric so that he/she may take remedial measures. But do not stop taking the medicine on your own or alter the dose without consulting your physician. Your physician should also know if you are pregnant, planning to become so or if you are nursing your baby. Share all information about your medical history including past instances of liver disorders, cardiac disorders like stroke or heart attack, renal impairment or liver disorders like hepatitis, cirrhosis or liver failure. Always store Uloric in a safe place away from the reach of children or pets and never share your medicine with anyone else. Store it in a cool and dry place which is not in direct contact with sunlight. Avoid storing Uloric in the bathroom. Ideal temperature for storing this medicine is 250 C.

Uloric Side Effects

Uloric has been prescribed to you by your physician as it is a safe medication without any significant side effects. However, like all medicines, some patients may experience certain discomforts while using this preparation while others may not. Seek emergency medical attention if you have an allergic reaction after taking Uloric like swelling of mouth, tongue, face; hives, rashes, difficulty in breathing or speaking etc. Some other minor side effects include nausea, dizziness or stiffness and swelling in the joints. Febuxostat (the primary ingredient in Uloric) may lead to an over-production of liver enzymes. This can lead to some serious side effects like persistent abdominal pain, yellowing of your eyes of skin, passing dark-coloured urine or a continuous feeling of nausea. Inform your physician immediately if you experience any such symptoms as your physician may then conduct a blood test to measure the level of liver enzymes. You must also contact your medical caregiver if you experience any of the following:

• General ill feeling accompanied by unusual sweating
• Unexpected weakness or numbness particularly on one area of your body
• A sudden onset of pain or heavy feeling in the chest region which is gradually spreading to your shoulders or arms
• If you are feeling dizzy and unable to see or speak clearly

Uloric Drug Interactions

If you are undergoing treatment with Mercaptopurine or Azathioprine Uloric will be contraindicated for you as the medications can interact with each other leading to a high concentration of plasma level that may become toxic. It is also be prescribed with care in patients undergoing treatment with theophylline. Apart from febuxostat, Uloric also contains several inactive ingredients which may interact with other medicines or preparations. Hence, inform your physician about any other prescription drugs you that you are taking presently. Share with him / her all information regarding your addictions to alcohol, nicotine or caffeine. Discuss freely about other non-prescription medications, health supplements, herbal preparations, vitamins and dietary supplements.

If you have any questions about buying discount Uloric online or any other prescription products you can contact our team of professional Patient Service Representatives or one of our pharmacists 24-7 by calling 1-800-226-3784.

Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

Uloric and/or Equivalents warnings, side-effects and general information